Quick Overview:
Amtas-M 50 is a fixed-dose combination antihypertensive containing a calcium channel blocker and a selective beta-blocker.
Amlodipine is a long-acting calcium channel blocker. It inhibits calcium influx into blood vessel walls, causing them to relax and widen. This directly lowers peripheral resistance and improves overall blood flow.
Metoprolol Succinate is a cardioselective beta-blocker delivered in a prolonged-release (PR) matrix. It works by blocking the effects of stress hormones on the heart, effectively slowing down your heart rate and reducing how hard the heart muscle has to pump. Together, they form a powerful combination: amlodipine handles the structural tightening of the blood vessels, while metoprolol safely controls heart rate and workload, protecting the cardiovascular system against morning spikes and long-term organ damage.
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Uses / Indications
Hypertension (High Blood Pressure): Combined therapy to manage elevated blood pressure when single medications fall short.
Angina Pectoris (Heart-Related Chest Pain): Reduces the frequency and severity of chest pain by optimizing oxygen supply to the heart.
Chronic Heart Failure & Arrhythmias: Helps reduce structural strain on the heart and manage irregular heart rhythms.
Key Benefits
Comprehensive 24-Hour Coverage: The prolonged-release metoprolol coupled with amlodipine ensures steady, around-the-clock protection against hypertension.
Palpitation Control: Metoprolol directly stops the racing heartbeat (reflex tachycardia) that amlodipine might otherwise trigger when expanding blood vessels.
Enhanced Exercise Tolerance: Minimizes the standard workload and oxygen demand of the heart muscle, enabling patients with angina to stay active with less risk of sudden chest discomfort.
As Directed by a Physician: Dosage is carefully adjusted based on the patient's individual blood pressure and pulse readings.
Headache, dizziness, or daytime drowsiness
Ankle Swelling (Peripheral Edema): A common response to fluid shifts caused by amlodipine
Bradycardia (an abnormally slow heart rate from metoprolol)
Flushing (sudden warmth/redness in the face, ears, or neck)
Mild stomach pain, nausea, or constipation
- Store in a cool dry place
- Keep away from direct sunlight
- Keep out of reach of children
- Read the label carefully before use